Thanks for enabling the creation of this Rana muscosa/unicorn hybrid for the Annual Meeting! 😂

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We exemplify the use of a structurally resolved interactome to study interface mutations and phosphorylation. 280 interfaces carry pathogenic variants, including mutations in TWIST1 linked with Saethre-Chotzen syndrome that likely disrupt the predicted interface with TCF4

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30: CONJUGATION

Sharing antibiotic resistance plasmids by conjugation has turned the much-ignored opportunist A. baumanii into a pathogen of repute. Carbapenemases for the win?

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Fun fact: As it turns out, there are only 3 out of 3000+ species of bats that are actually vampires! 🦇

In addition, blood is actually a terrible source of nutrition, with potential pathogens and overloaded with iron!

Therefore, it clearly only makes sense that he eats souls👻

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28: ADHESION

Infectious disease can be caused by mere stickiness, as with misfolded Prion proteins. We all have Prions, but if infectious misfolded Prions stick to them, they mis-fold too & the stickiness spreads.

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26: COMPETITION

Dengue fever virus has 5 serotypes that compete for hosts. Primary infection with 1 makes further infection with another much more dangerous. So it’s a real killer competition!

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25: TRANSPOSON

Also known as jumping genes, they’re a handy tool in a many pathogen's toolkit. Transposons give Cryptococcus neoformans the genetic room it needs to adapt & resist antibiotics during infection.

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24: ZOONOTIC

Sometimes we're incidental hosts to pathogens. Ebolaviruses mostly infect non-human primates & bats. Our Ebola outbreaks start w. a spillover from these animals, before human to human spread takes over

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20: LUMINESCENCE

Yes, there are luminescent pathogens too... Vibrio harveyi causes luminescent vibriosis in farmed shrimp. This may involve widespread necrosis in their appendages, but what a pretty colour!

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18: MOTILITY

Proteus is a catheter opportunist with a bullseye motility pattern, due to cycling btw vegetative & swarmer states. A switch to swarming causes massive elongation, many more flagella & all the nasties!

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Natural enemies of environmentally mediated parasites and pathogens abound in nature. Can we do better to identify, measure, and harness these ecosystem services? propose 3 reasons why natural enemies deserve more attention for sustainable disease control.

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14: CHEMOTAXIS

Helicobacter uses chemotaxis to swim towards some tasty sugars on the lining of the stomach, and finds its home there for life

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12: DIVISION

In their infectious form, these brain-eating amoebae can divide without breaking up their nuclear membrane, in a process called promitosis.

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10: DEFENCE

As their defence, Bordetalla pertussis attacks our immune defences in the lungs, so the airways don’t produce mucus. This causes the coughs to make a characteristic whooping sound

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5: LYSIS.

To spread, viruses (ABCDEFG…) explode their host cells ('cell lysis') to leave them because they don’t need host membranes to make new virions.

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4: DORMANCY. Bacillus anthracis spores can lay dormant for decades, as tested on Gruinard Island in Scotland in 1942. Apparently safe now!

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3: FLAGELLA. Trichomonas is a that causes bacterial vaginosis w. FIVE & an axostyle. No one knows what the 5th one does.

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Who let the cats out? Outdoor cats are 2.77 times as likely as indoor-only cats to be infected with pathogens https://t.co/kxi01ikB42 |

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2: CELL. causes blindness and but it needs a host cell to turn it’s tiny elementary bodies into something that can replicate.

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Fellow pathogens! We have our royalty token in place.

Holders of our OG Viruses will be awarded their shares of royalties, starting from when the CNFT marketplaces add the functionality.💰💰

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