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66 yo F with L hip pain s/p trauma.
Hx: SOB, itchiness, hives, vomiting
AGGRESSIVE SYSTEMIC MASTOCYTOSIS
- CD25+, CD117+
- Kit Gene Exon 17 mutation+
- Spindle cells w/ granular cytoplasm
- Mast cells replacing marrow (causing Fx)
#bstpath #hemepath #pathology #pathtwitter