//=time() ?>
Using intraoperative microelectrode recordings of basal ganglia neurons during a supine stepping task, Gulberti et al. investigate the contribution of subthalamic and nigral neurons to freezing of gait in Parkinson’s disease. https://t.co/rIv5Uhxh7P
Pineda-Pardo et al. show that striatal dopaminergic denervation in early Parkinson’s disease follows a somatotopic pattern, beginning with the upper limb representation in the putamen. The changes correlate with the evolution of motor features. https://t.co/fMArpLcsFg
Carlstrom et al. review current understanding of the glymphatic system, including its structure, function and relevance to human neurological disease, and discuss the opportunities to harness glymphatic science for therapeutic applications. https://t.co/orqUrwse0E
Young et al. review the past, present and future of advances in clinical neuroscience relating to disorders of consciousness, including key challenges associated with assessing residual consciousness. https://t.co/o8BcKQCBCK
Mallas et al. report that traumatic brain injury patients with episodic memory impairment show abnormal activation within key attentional brain networks compared to patients with normal memory function. https://t.co/A9HgGnK4R3
Are emotions innate or does their expression & recognition depend on contextual knowledge? Bertoux et al. use neuroimaging in patients with the semantic variant of primary progressive aphasia to explore the basis of emotion recognition. https://t.co/FmYiAIr5MF
Hippocampal hyperactivity is a promising neuromarker for #Alzheimer’s disease. Using neurofeedback and virtual reality, Skouras et al. explore how elevated amyloid and tau affect functional networks involved in hippocampal self-regulation. https://t.co/cRFI6kB7cQ
Vascular reserve in brain resilience: pipes or perfusion? New scientific commentary by Wiesmann & de Leeuw https://t.co/P3LlM6hguM
Betthauser et al. show that individuals with elevated levels of both pathological beta-amyloid and tau show faster cognitive decline during late middle-age than those with one or no elevated biomarkers. https://t.co/j5PoSDRNbl
Tyzack et al. report that FUS protein – previously thought to mislocalise only in ALS patients with FUS mutations – is also mislocalised in many cases of sporadic ALS. https://t.co/Cnt5Difd02