Noah Bradleyさんのイラストまとめ
@Dr__AminoFollow @Dr__Aminoさんをフォローする
Postdoc @ Northwestern University; Yuan He lab. Structural biologist studying macromolecular machines on genes through cryo-EM of DNA repair complexes ❄️🔬🧬⚙️
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Models of how CalC interacts with CCM suggest the sugars bind within a central pocket of the protein, while the sacrificial peptide bond resides on a loop which is positioned to interact with the radical portion of CCM (A & B) (PDB: 2L65).
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Very cool digital rendering of DNA interstrand crosslinks (red sticks) and the DNA repair enzyme (YcaQ; red blob) we characterized performing unhooking of those ICLs (yellow sticks).
We've got two pubs on this enzyme superfamily coming up!
Artwork prepared by @ArtLab_Vandy :)
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