Frequent Enough Isaac Factsさんのイラストまとめ

In the art for the Binding of Isaac: Isaac’s Tears White Grape Pineapple G-FUEL mix, the character Fiend from the Fiend Folio MOD appears.

The artist who made the amazing art for the mixture is a developer for the Fiend Folio MOD, so they snuck him in there as a neat easter egg.

The sounds Embyros, Babies, and Wall Huggers make are from the game World of Goo! https://t.co/KyfHbmaT9k

Also, they used to look like this???

The Binding of Isaac: Repentance's desktop icon changes whether you're using a Tainted Character or not.

The boss Big Horn has an odd-looking unused bomb in his sprite sheet.

It is unknown what this bomb would've been used for, but it may have created a big explosion.

Tainted Jacob's Birthright description was originally "There is no escape", but was later changed to "It's not yours."

This is a reference to Jacob and Esau's Birthright description being "What's yours is mine"