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The Department of Pathology at Johns Hopkins University
pathology.jhu.edu

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An elderly patient presents with a parotid mass. What is your diagnosis? Answer and explanation to follow!
Thank you to our medical student who recently rotated with us, , for helping prepare this case!

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A pediatric patient who was treated for Ewing sarcoma with chemotherapy now presents with a retroperitoneal node enlargement. What is your diagnosis? Answer and explanation to follow.

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Answer: Pleomorphic hyalinizing angiectatic tumor (PHAT) arising from hemosiderotic fibrolipomatous tumor (HFLT). Both tumors have TGFBR3-MGEA5 gene fusion. Peripheral areas of PHAT can be identical to HFLT.

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