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Renal Pathologist at Cedars Sinai Medical Center. Views are my own.

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They say that "endocapillary hypercellularity (ECH)" has poor interobserver reproducibility among pathologists. I wish they could all be this easy. 8 yo F with newly dx'ed SLE, now with Class IV LN, diffuse ECH, few "wire loops" and "hyaline thrombi" (I still hate this term!)

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When it's NOT just diabetes: 78 yo M with DM/HTN and mild proteinuria, now with 7 g protein and worsening renal function. Diffuse/nodular diabetic glomerulosclerosis, FSGS, and (SURPRISE) membranous nephropathy, THSD7A+. Diabetes: To biopsy or not to biopsy? THAT is the question.

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