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Pranlukast, a drug for treating asthma arrives in the PDB today, bound to it target the cysteinyl leukotriene receptor.
Solved @esrfsynchrotron and published in @ScienceAdvances, it's one of the new structures today at https://t.co/54E03LeH5m
It's Wednesday again, so even more #openaccess protein structures available! This enzyme is one of them, published in @NatureCatalysis by P.Leadlay et al @CamBiochem it catalyses the formation of antibiotic tetronasin
https://t.co/54E03LeH5m
#thanksOA
In @LSAjournal, @garagao et al describe structural homology between cytochrome C oxidase assembly factor Coa6 (green) which is implicated in mitochondrial disease, and cox6b (brown) a component of cyctochrome C oxidase itself! Discovered using #PDBeFold
https://t.co/BtgnT76jzO
A study in @TheLancet shows administering tranexamic acid to head-injury patients could save lives by stopping bleeding. It's an inhibitor of urokinase plasminogen activator, binding in the active site, as seen here:
https://t.co/wF4iVMQDYE
In honour of Monday's #NobelPrize announcement, erythropoietin is @ensembl's #geneoftheweek
Find out what is known structurally about the gene product on the #PDBeKB page:
https://t.co/UWKft7xNPI
Henry from @ImpingtonVC painted this #PDBart for our calendar this month. It's inspired by the first protein structure to be determined, at @MRC_LMB.
(He had a whale of a time making it)
https://t.co/doJrX3x2Ph
A nuclease from a Svalbard intertidal zone needs a disulphide between subunits for optimal activity.
#structuresonthecover of @FEBSOpenBio from scientists @UiTromso
https://t.co/BKxQtfmo2E
A novel fold described @jbiolchem! Using #PDBeFold, Ndi et al identify cytochrome b chaperone Cbp3 as a previously unseen protein fold.
https://t.co/dWW0PxqZ9n
Genomes of giant marine viruses encode many proteins with no known homologues, but this viral rhodopsin, solved by scientists @MBARI_News et al and published in @PNASNews certainly has homologues!
One of the new structures today at https://t.co/54E03LeH5m
Constantin Fahlberg was granted a patent #OTD in 1885 for the use of artificial sweetener saccharin, which is found bound to 3 different proteins in the PDB
https://t.co/Fy0qMiJUmJ