These Two Have Appeared In The Same Thingさんのイラストまとめ

Rob Dyrdrek and Isaac Clarke (Dead Space) have appeared in Skate 3 together

Akira Yuki (Viruta Fighter) and Holo (Spice and Wolf) appear in Dengeki Bunko: Fighting Climax together

Thanos (Marvel Comics) and Peter Griffin (Family Guy) both appeared in Pinball FX3

Marie (Splatoon) and SpongeBob SquarePants appeared in Splatoon together

Kirby and Hatsune Miku (Vocaloid) appeared in Taiko no Tatsujin: Drum 'n' Fun! together

Darth Vader (Star Wars) and Amy (Soul Calibur) appeared in Soul Calibur IV together

Isabella Garcia-Shapiro (Phineas and Ferb) and Red Skull (Marvel Comics) appeared in Phineas and Ferb: Mission Marvel together

Sol Badguy (Guilty Gear) and Hatsune Miku appeared in Brave Frontier together

Akatsuki (Akatsuki Blitzkampf) and Sion Eltnam Altasia (Melty Blood) appeared in UNDER NIGHT IN-BIRTH together

Hatsune Miku and Yu Narukami (Persona) appeared in Persona 4: Dancing All Night together