David S. Goodsell 🏳️‍🌈さんのイラストまとめ

Finished the "Insulin Release" painting this morning. I'll be showing it at the @ACAxtal meeting in Portland, and I'll put a full-size file at PDB-101 @buildmodels when I get a few free moments. Insulin crystal in yellow, fused vesicle and cell membranes in green, ECM in purples.

Like everybody else in the world of science, I've been having fun exploring the database of AlphaFold structures. Here are (subunits of) a few proteins that show up often in my paintings. It (amazingly) gets all the bits and pieces right, but doesn't quite yet get the biology.

Just put a few new paintings @buildmodels: myoglobin packed into a whale muscle cell and a rework of the extracellular matrix painting from my book (both for the PDB50 celebration), and a red blood cell membrane and cytoskeleton. They're available at: https://t.co/lUPHWigjT3

We just put updated versions of CellPAINT on SourceForge https://t.co/10APDQAZ4a to fix some problems with saving and restoring work. Please let us know if you're still encountering problems on your contest entries!

Just finished the red blood cell painting--hemoglobin in red, blood plasma in yellows at the top, and the amazing membrane/cytoskeleton in purple.

Here's the ferritin design--entry 2fg8 @buildmodels

The February Molecule of the Month @buildmodels is up. A topical subject: coronavirus proteases, including a new structure from the 2019-nCoV coronavirus. https://t.co/np24lZ8HLs

Finished up the virus--just have to add some depth to the surrounding background!

Getting to work on the Coronavirus painting this morning--started with the "corona" of spike S proteins. M proteins next, if I can find some time later today.

Trying to decide if I'm going to show the E protein in the coronavirus picture. Everything I'm reading says that most of it stays in the ER/Golgi, but a few may end up in virions. Hmm.