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lapis lazuli from steven universe is canonically genderless! she also shows many symptoms of PTSD, depression, and other disorders
(requested) handy from happy tree friends is an amputee
(requested) shinji ikari from neon genesis evangelion is bisexual with depression and anxiety. he also shows symptoms of bpd and ptsd
trixie from my little pony friendship is magic is confirmed to be trans!
kelsey jannings from bojack horseman is canonically a lesbian!
(this series contains disturbing content)
(requested) xada from lovebot is canonically trans and mlm! he also has a prosthetic leg!
avatar kyoshi from the avatar franchise is canonically bisexual!
(requested) catra from she ra and the princesses of power is canonically a lesbian and shows symptoms of ptsd, bpd, and depression
(requested) korra from avatar is canonically bisexual and has PTSD and depression
garnet from steven universe is canonically genderless and a lesbian! or just. is lesbianism technically? she is also stated to have depression