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Syed Z. Aliさんのイラストまとめ


Director of Cytopathology at Johns Hopkins. Past-President, American Society of Cytopathology (ASC). President-Elect, International Academy of Cytology (IAC).

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Just an impressive example - A loose fragment of "Physaliphorous" cells surrounding a binulceated cell with an INCI. Sacral mass - "Chordoma"

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"The Denuded Nuclei" - Some of the most common cytomorph features that I've used over the years to dx "ACINIC CELL CA" of the salivary glands - Perivascular nesting, granular to vacuolated "histiocyte-like" cytoplasm, BARE NUCLEI and a characteristic background granular coating.

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"Useful Lesson in Thyroid FNA". An intimate mixture of malignant cells and skeletal muscle most often means an extra thyroidal extension, like in this case (commonly occurs with Anaplastic CA). Although, there is some pleomorphism here, the final Dx in this case was Papillary CA.

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Who says life in Thyroid Cyto is easy - "Una Vita Difficile". Here, the initial impression would be "Papillary CA with thick colloid". However, the 2nd image clearly shows orange to be keratin and NOT colloid. FNA was called PD CA with Sq features. F/U Anaplastic CA with Sq diff.

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"Super Inclusions" - Although typically described in Tall Cell Variant of Papillary Thyroid CA (PTC), these so-called "soap bubble" intra nuclear cytoplasmic pseudo inclusions (INCIs) can be seen in classic PTCs (as in this case).

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It's EXTREMELY RARE to have intranuclear cytoplasmic inclusions (INCIs) in a Hurthle cell neoplasm on FNA. When faced with oncocytic cells containing INCIs, it's best to think first of a Papillary CA (conventional or oncocytic variant) followed by Medullary CA. Histo f/u - PTC

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