Ashley & Brooke Barlow PharmDさんのイラストまとめ
@theABofPharmaCFollow @theABofPharmaCさんをフォローする
For the love of teaching clinical pearls & infographics ll MSL Pulm || MSL Oncology II @CritCareMed II Views are our own
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Remember hallmark ADE of irinotecan(diarrhea)➡️I-RAN🏃♂️-TO-the-CAN🚽
Genomics plays a🔑role
SN-38(active)♼UGT1A➡️SN-38G(inactive)🛑
Isoforms in UGT1A*28⤴️SN-38 ⤴️neutropenia🦠&diarrhea🚽
Fun Fact:Mechanism of early diarrhea➡️🚫acetylcholesterases Rx💊Atropine!
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