This week: 509 SARS-CoV-2 structures freely available in the PDB archive https://t.co/C8psgBQVrw

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There are 210 new entries in the first release of the 50th year of the PDB, including this cryoEM structure of NAD+ hydrolase SARM1 (7cm7), involved in nerve cell degeneration in response to injury, published in . Find all the new entries at https://t.co/54E03LeH5m

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Day15

Toll-Like receptors, the brave sentinels of our immune system! They act in the first line of defence against bacteria and viruses, triggering an inflammatory fight against intruders



inspired by PDB 3fxi

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誠一郎のネトプリ予約したよ!
セブンイレブン、フォト用紙(Lサイズ)
1枚目: Y5PDB8TT
2枚目:LPSU9KTD です!

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Dexamethasone and Cytokine Storms: Preventing too much of a good thing during SARS-CoV-2 infection

New feature in PDB-101's Resources to Fight the COVID-19 Pandemic https://t.co/vNStgOYtuW

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Congratulations to PDB depositors Emmanuelle Charpentier and Jennifer A. Doudna on the Nobel award for the development of a method for genome editing.

Cascade and CRISPR help bacteria remember how to fight viral infection. More at Molecule of the Month https://t.co/39SeogATE3

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6 new SARS-CoV-2 structures in the PDB this week (321 total). Access these structures and more at https://t.co/C8psgBQVrw
When will we reach 400?

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A new representation of polymeric carbohydrates has been introduced in the PDB. This new representation includes information about carbohydrate linkages and standardised nomenclature. To find out more visit the wwPDB page at https://t.co/5CTanOH2yM 1/2

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This week's PDB release has almost 300 new entries, including this O-methyltransferase structure from the strawberry, published in . View all the new PDB entries at https://t.co/54E03LeH5m

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Changing character names on PDB until I get IP banned 💖 here’s the highlight reel ✨

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There are 230 new entries this week, including this janus kinase structure, bound to the dermatological drug Delgocitinib, published in . View all the new PDB structures at https://t.co/54E03LeH5m

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in 1943 was American chemist Richard Smalley. He shared the Nobel Prize in Chemistry with Harry Kroto and Robert Curl for their discovery of buckminsterfullerene or "buckyballs". There are 3 entries in the PDB with buckyballs! Find them at https://t.co/aNHm3pLY6x

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Newly available trajectories for the SIRAH-CoV2 initiative:

S1 Receptor Binding Domain in complex with human antibody CR3022 (PDB 6W41) https://t.co/QqE6AdP0An

NSP16 - NSP10 Complex (PDB 6W4H) https://t.co/wrqF6pJDPX (image below)

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昨日、新型コロナSARS-CoV-2のスパイク蛋白(PDB:6VSB)と似ている形状で、タンブラーグラスとかア・バオア・クーとか書いたけど、その後「もっと似ているものがあったよなあ・・・」と思っていた。
そして夜半過ぎに思い出した。

 縄文時代の火焔土器だ

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This week's release sees another 16 structures of the main protease with different fragments bound, solved by researchers at . All this structural information and more is available at our data portal: https://t.co/N6oiomu2ZC

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Watercolor & ink painting of the COVID-19 main protease


-- based on PDB structure 6LU7, 2019-nCov coronavirus 3CL hydrolase (Mpro)
https://t.co/2fTwfVkcHa

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New in this week's release is this structure of the RNA polymerase (7btf). Remember, you can find all available PDB data on including ligand binding and interaction sites, at our PDBe-KB COVID-19 data portal: https://t.co/NBFmsXI9VW

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The earliest PDB example of ribonuclease was available in 1979 (now PDB structure 5rsa), but had been described in scientific literature previously. Deposition of structure data was not always a requirement for publication
Ribonuclease: https://t.co/QWHirE051A

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Remdesivir, Sofosbuvir
NS5B RdRp with Sofosbuvir (4WTG.PDB)
SARS RdRp homology model (1SXF.PDB)

核酸の塩基をミミックしている部分に違いがあるな!
RdRp 同士、フォールディングは近いが活性部位には個性がある。

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PDB images often appear in textbooks, flyers and posters. Bonnie Hall () describes how initial interest in these images can be leveraged to engage students in a variety of chemistry classes https://t.co/MymAigk6Ms

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