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● Focus on C797S “ cis “ mutation As for the 4th generation TKIs, four candidates have been reported so far. 1st. Jia et al. Nature 2nd. To et al. Cancer Discov 3rd. BLU-945 ESMO 2020 abst. #1296P 4th. BLU-701 AACR 2021 abst. #1262P