Which of the following are true regarding this bone tumor?
A. More common in axial skeleton than appendicular skeleton.
B. Most are asymptomatic and incidental findings in adults.
C. No recurrent genetic alterations.
D. All of the above.

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Intranodal palisaded myofibrablastoma. Hemorrhages, collagenous bodies, palisades of bland spindle cell. Ddx with Kaposi sarcoma and schwannoma.

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🔴Undifferentiated Embryonal Sarcoma of the liver
➡️Rare, mostly youngsters (<20s)
➡️usually large tumors
🔬Mixture of pleomorphic and round to spindle cells
🔬Variably mixoid background
🔬Hyaline globules
🧪Unspecific phenotype (MYF4➖)
🧬19q.13 rearrangement (subset)

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🔴Schwannoma
📚Benign nerve sheath tumor of schwannian origin
🔬Encapsulated
🔬Biphasic: dense areas(Antoni A) +loose hypocellular areas(Antoni B)
🔬Variants: cellular, plexiform, melanotic, ancient, epithelioid, reticular
🧪S100/SOX10➕(diffuse)
🧬22q12 loss (NF2)

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🍪🍪🍪🍪🍪🍪🍪🍪🍪🍪🍪
🍪🍪🍪🍪Giant Cells🍪🍪🍪🍪
🍪🍪🍪🍪🍪🍪🍪🍪🍪🍪🍪

Part1️⃣

1/6
What better way to kick-start the new year🎇than with a tweetorial/#RolaCoaster ?
Specifically made for the family💝
Hope you enjoy the🎢!

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A case with lipoid variant histology in urothelial carcinoma and a case of pleomorphic liposarcoma...look very similar, can you tell which is which?

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