A warthin-like mucoepidermoid carcinoma of the parotid gland with CRTC1-MAML2 fusion. Noted that the lining are multilayered/stratified rather than bilayered.

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50 yo female with upper respiratory tract symptoms and a loose molar. CT shows expansile maxillary soft tissue mass (4 cm) with bone destruction.

Case provided by

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Pediatric Warthin-like Mucoepidermoid Carcinoma: Report of Two Cases with One Persistent/Recurrent as Conventional Mucoepidermoid Carcinoma

https://t.co/PFOcPOa5RN

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Secretory Carcinoma of Thyroid
📍Recently described (case#10)
📍ETV6-NTRK3 fusion
📍Commonly misinterpreted as PTC with oncocytic feature
📍Cribriform, solid, trabecular
📍Eosinophilic cells, vacuolated cytoplasm
📍+ve: S100, Mammaglobin, -ve: TTF-1, TG

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70 yo man with right parotid gland mass. A great example of Salivary Duct Carcinoma, Key features: Comedonecrosis, “Roman bridge”, numerous mitoses, AR+, CK7+, CK5/6-, p63-.

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