# quantitative proteomics tau alzheimer disease geneoftheweek pdbekb

A high-resolution map of post-translational modifications on multiple of reveals the importance of PTMs in Resource article online now! https://t.co/Nn9I6FeG9P

8 22
2020-11-13

Ectodysplasin-A is recognised by EDAR, 's and involved in signalling cell death. There are 2 structures in the PDB, representing 2 isoforms - binding to either EDAR or EDA2R. View the structures at https://t.co/JIS2po2O5u https://t.co/dgU0HbmMGr

1 2
2020-01-28

Remember hallmark ADE of irinotecan(diarrhea)➡️I-RAN🏃‍♂️-TO-the-CAN🚽
Genomics plays a🔑role

SN-38(active)♼UGT1A➡️SN-38G(inactive)🛑
Isoforms in UGT1A*28⤴️SN-38 ⤴️neutropenia🦠&diarrhea🚽

Fun Fact:Mechanism of early diarrhea➡️🚫acetylcholesterases Rx💊Atropine!

6 27
2020-01-21