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This abysmal Health Hotline commercial for knee braces. The ad itself is mostly just mind-numbingly boring, but the animation is what makes it horrible: it's almost entirely made up of static stock clip art with barely-animated mouths flapping randomly
While not hated outright, Simpsons writer Bill Oakley once noted Marge was the most difficult character of the Simpson family to write episodes for, to the point they were often relegated to new writers as a test of their story-writing skills.
Friz Freleng wasn't fond of Elmer Fudd, stating the character was too dumb and pitiful, thus Bugs Bunny's usual trickery on him made him look too sympathetic and caused a delicate dance to avoid Bugs look unlikable.
Several Warner Bros. staff grew to hate Porky Pig, particularly director Frank Tashlin, citing him to be "a terrible character" who was less charismatic and flexible to the franchise's trademark slapstick as later additions such as Bugs and Daffy
Seth MacFarlane stopped voicing Tim the Bear halfway into Season 3 of The Cleveland Show because he found the character annoying and unfunny.