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🔴Undifferentiated Embryonal Sarcoma of the liver
➡️Rare, mostly youngsters (<20s)
➡️usually large tumors
🔬Mixture of pleomorphic and round to spindle cells
🔬Variably mixoid background
🔬Hyaline globules
🧪Unspecific phenotype (MYF4➖)
🧬19q.13 rearrangement (subset)
#BSTPath
🔴Schwannoma
📚Benign nerve sheath tumor of schwannian origin
🔬Encapsulated
🔬Biphasic: dense areas(Antoni A) +loose hypocellular areas(Antoni B)
🔬Variants: cellular, plexiform, melanotic, ancient, epithelioid, reticular
🧪S100/SOX10➕(diffuse)
🧬22q12 loss (NF2)
#BSTpath