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President, Max Planck Society
@maxplanckpress
mpg.de/de/praesident/…

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# covid19 remdesivir coronavirus

We show how the drug inhibits replication: Remdesivir stalls the viral polymerase by posing a translocation barrier, retaining the RNA 3'-end in the substrate-binding site, and hindering RNA proofreading. Preprint: https://t.co/q7Fgblhm3m

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2020-10-29