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One of the first protein structures solved was that of haemoglobin, earning Max Perutz a share of the 1962 Nobel Prize in Chemistry. This 38th #PDB50structures transports oxygen around our body through our bloodstream: https://t.co/Q5hvnzeWS1
20 new SARS-CoV-2 structures this week, 841 this year (shown), for 1629 total available in the PDB.
Explore them all at https://t.co/q3UBxbZoaF
14 new SARS-CoV-2 structures this week, 821 this year (shown), for 1609 total available in the PDB.
Explore them all at https://t.co/q3UBxbHMM5
Serotonin is a molecule thought to affect mood and has been linked to depression. Our 28th #PDB50structures is the structure of the serotonin receptor bound to serotonin, forming an 'open' state: https://t.co/HtaXuVNczr
Glucose moves through blood, powering cells throughout the body. High glucose levels can cause chronic problems associated with diabetes mellitus. PDB structures reveal how glucose levels are regulated in the body #WorldDiabetesDay Explore: https://t.co/Huwgmx0N0t
20 new SARS-CoV-2 structures this week, 807 this year (shown), for 1595 total available in the PDB.
Explore them all at https://t.co/q3UBxbZoaF
Structure of the vaccinia virus transcription initiation complex determined by CryoEM (PDB code: 7AOZ)
New #rendering by @fenguita (Paco.Enguita on Instagram) made with #ProteInimager.
Here is the 3D view: https://t.co/ES1UBdZoYi
#molecularart
17 new SARS-CoV-2 structures this week, 787 this year (shown), for 1575 total available in the PDB.
Explore them all at https://t.co/q3UBxbZoaF
Cytochrome P450s are our 14th #PDB50structures. This heme-containing superfamily are the terminal enzymes in a host of electron transfer chains, for example this structure 2cpp: https://t.co/zbiKTjscBP
Day 26/31
I’m featuring molecules in #pdb this #inktober
Prompt: “Connect”
Here is ubiquitin (1UBQ). I could not skip this classic! It connects to its targets, it connects to itself, it connects molecules that otherwise would not find each other…
@PDBeurope @PDBeurope
Day 25/31 of #inktober
Prompt Splat
I’m featuring molecules in #PDB
SEA domain of mucin 1 (pdb 2ACM). Mucins provide framework of the mucus fluid, which protects all mucosal epithelial surfaces. I imagine it’s pretty slimy and probably lands with a splat!
@buildmodels @PDBeurope
Our third #PDB50structures is the most prevalent in the PDB archive. There are over 1000 structures of Lysozyme, an antimicrobial enzyme, in the PDB archive. View all the structures of chicken Lysozyme at #PDBeKB: https://t.co/77Hp4cIHQy
Our next #PDB50structures is the first structure of a protein from SARS-CoV-2, the virus responsible for COVID-19. Solved by Prof. Zihe Rao's group, it kickstarted structural studies supporting the fight against COVID-19. View it at https://t.co/Oaa1hgK2Kp
Happy birthday PDB! A few entries in there with my name on (along with the amazing structural biologists who actually turned my xtals into data). My absolute favourite is this one: https://t.co/hqcEWKQYzu
which took me years to crystallise and also is 😍 #PDB50 #glycotime https://t.co/IQgJ7Rw03F
Celebrate Irving Geis' birthday (October 18, 1908) with a tour of the Geis Digital Archive at PDB-101: https://t.co/bklsGIJ2C0 #PDB50 #SciArt
It's #CardCollectionDay! Take the https://t.co/VNJJGPxgZr User Survey at https://t.co/xZPFhk4X4m to be entered in a drawing to win a set of #pdb50 Structural Biology Playing Cards
Day 11/31
Prompt “sour”
I’m featuring molecules in #pdb for this year’s #inktober
Here is Curculin, which has an intriguing property of modifying sour taste into sweet taste.
#pdbart @buildmodels @PDBeurope
PDB Pioneers: A dozen historic structures set the foundation for the PDB archive. More at Molecule of the Month: https://t.co/UpxAnVmZcn #PDB50
Our structural aligner Foldseek can now automatically download databases in a single command. We provide the PDB (#PDB50) and Alphafold DB. You can download Foldseek here: https://t.co/HVRSi3ycX3
foldseek databases PDB pdb tmp
foldseek easy-search query.pdb pdb aln.m8 tmp
Visit PDB-101 to explore connections between Nobel Prizes and 50 years of open access to the PDB archive #PDB50
https://t.co/AvwgG1MM33