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Emmanuelle Charpentier and Jennifer Doudna were awarded the 2020 Nobel Prize in Chemistry for their work on CRISPR-Cas9. This system has been adapted for use in gene editing and is our 46th #PDB50structures. View the structure at https://t.co/qv7xiIOkWc
Our 42nd #PDB50structures are Tau protein fibrils from Alzheimer's patients, studied using cryoEM. This structure highlights the binding of fluorescent tracer molecule APN-1607: https://t.co/v8AnNpFzAA
One of the first protein structures solved was that of haemoglobin, earning Max Perutz a share of the 1962 Nobel Prize in Chemistry. This 38th #PDB50structures transports oxygen around our body through our bloodstream: https://t.co/Q5hvnzeWS1
Serotonin is a molecule thought to affect mood and has been linked to depression. Our 28th #PDB50structures is the structure of the serotonin receptor bound to serotonin, forming an 'open' state: https://t.co/HtaXuVNczr
Cytochrome P450s are our 14th #PDB50structures. This heme-containing superfamily are the terminal enzymes in a host of electron transfer chains, for example this structure 2cpp: https://t.co/zbiKTjscBP
Our third #PDB50structures is the most prevalent in the PDB archive. There are over 1000 structures of Lysozyme, an antimicrobial enzyme, in the PDB archive. View all the structures of chicken Lysozyme at #PDBeKB: https://t.co/77Hp4cIHQy
Our next #PDB50structures is the first structure of a protein from SARS-CoV-2, the virus responsible for COVID-19. Solved by Prof. Zihe Rao's group, it kickstarted structural studies supporting the fight against COVID-19. View it at https://t.co/Oaa1hgK2Kp
Happy birthday PDB! A few entries in there with my name on (along with the amazing structural biologists who actually turned my xtals into data). My absolute favourite is this one: https://t.co/hqcEWKQYzu
which took me years to crystallise and also is 😍 #PDB50 #glycotime https://t.co/IQgJ7Rw03F
Celebrate Irving Geis' birthday (October 18, 1908) with a tour of the Geis Digital Archive at PDB-101: https://t.co/bklsGIJ2C0 #PDB50 #SciArt
It's #CardCollectionDay! Take the https://t.co/VNJJGPxgZr User Survey at https://t.co/xZPFhk4X4m to be entered in a drawing to win a set of #pdb50 Structural Biology Playing Cards
PDB Pioneers: A dozen historic structures set the foundation for the PDB archive. More at Molecule of the Month: https://t.co/UpxAnVmZcn #PDB50
Our structural aligner Foldseek can now automatically download databases in a single command. We provide the PDB (#PDB50) and Alphafold DB. You can download Foldseek here: https://t.co/HVRSi3ycX3
foldseek databases PDB pdb tmp
foldseek easy-search query.pdb pdb aln.m8 tmp
Visit PDB-101 to explore connections between Nobel Prizes and 50 years of open access to the PDB archive #PDB50
https://t.co/AvwgG1MM33
Just put a few new paintings @buildmodels: myoglobin packed into a whale muscle cell and a rework of the extracellular matrix painting from my book (both for the PDB50 celebration), and a red blood cell membrane and cytoskeleton. They're available at: https://t.co/lUPHWigjT3
Download our latest #PDB50 treat with cards designed by @dsgoodsell https://t.co/mEUqTTxR6t
We conclude our countdown towards #PDB50 with a key structure of 2020 – the structure of inhibitor-bound #SARSCoV2 MPro. Published 2020 as 6Y2F in Science, this is one of the first ever SARS-CoV-2 protein structures! https://t.co/KK3Pa5bz16
#PDB50 @HZBde @buildmodels @PDBeurope
7 new SARS-CoV-2 structures this week, 365 this year (shown), for 1154 total in the PDB. https://t.co/q3UBxbHMM5
Just over 1 week left to a) enter the CellPAINT contest with your vaccine/PDB50 images & b) register for the inaugural PDB50 symposium. More: https://t.co/BtxwFIj8TH
14 new SARS-CoV-2 structures this week, 358 this year, for 1147 available in the PDB. Explore them all at https://t.co/q3UBxbHMM5
~2 weeks left to a) enter the CellPAINT contest with vaccine/PDB50 images & b) register for the May 4-5 PDB5 event. Details: https://t.co/7krBeaG0U3