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15/365 : Translocation spell part. 1

10 91
2022-01-16

AVP binds to the V2 receptor & enhances NaCl reabsorption (in the TAL) which increases interstitial osmolality

AVP also stimulates AQP2 translocation to the apical plasma membrane from intracellular storage vesicles

https://t.co/7UxfZVUU91

7 11
2021-11-18

We show how the drug inhibits replication: Remdesivir stalls the viral polymerase by posing a translocation barrier, retaining the RNA 3'-end in the substrate-binding site, and hindering RNA proofreading. Preprint: https://t.co/q7Fgblhm3m

92 310
2020-10-29

Hard Man Vs "Tele" (Translocation Droid)

Fun fact: Hard Knuckle is actually as effective as Hard Man's other weakness, "Magnet Missile", with both dealing 4 points of damage. Smart choice for Tele for "tele-reflecting" the knuckle back to the sender!

1 3
2020-07-19

Following our recent publication on the light-driven sodium pump KR2, I prepared my first (ever) animation on the mechanism of Na+ translocation. All 5 protomers can bind sodium simultaneously! Feedback is welcome😉

11 64
2020-05-04

Happy Wednesday! This week's case is a circumscribed parotid mass.

What is your diagnosis? 🔬

What is the characteristic associated translocation and gene fusion?

61 113
2020-03-12



A case I showed at yesterday’s STR Webinar:

Procedure: right subclavian-to carotid translocation for focal, severe stenosis close to origin of subclavian artery.



Explanation in a few days :-)

1 1
2020-02-01