# nephpearls covid19 remdesivir coronavirus art surreal edsax photoart sf postmodern fiction contemporary 1_unlimited sciencefiction transmitter rhodopsin pymol iontransport retinal

15/365 : Translocation spell part. 1

10 91
2022-01-16

AVP binds to the V2 receptor & enhances NaCl reabsorption (in the TAL) which increases interstitial osmolality

AVP also stimulates AQP2 translocation to the apical plasma membrane from intracellular storage vesicles

https://t.co/7UxfZVUU91

7 11
2021-11-18

We show how the drug inhibits replication: Remdesivir stalls the viral polymerase by posing a translocation barrier, retaining the RNA 3'-end in the substrate-binding site, and hindering RNA proofreading. Preprint: https://t.co/q7Fgblhm3m

92 310
2020-10-29

Following our recent publication on the light-driven sodium pump KR2, I prepared my first (ever) animation on the mechanism of Na+ translocation. All 5 protomers can bind sodium simultaneously! Feedback is welcome😉

11 64
2020-05-04